Pyelonephritis

Pyelonephritis is an inflammation of the kidney tissue, most often bacterial, in which the calyces and the renal pelvis are involved in the process. The disease can run an acute course, with lower back pain, fever and changes in urine tests, or a chronic course, with periodic exacerbations. Diagnosis and treatment are handled by a urologist or nephrologist, sometimes with the involvement of a physician. At the first signs, it is important not to postpone a visit to a specialist.

Which doctorNephrologist, also — urologist
UrgencyDo not delay
Reviewed byMedical editorial team
Updated

With typical symptoms such as lower back pain and a rise in temperature, you should see a doctor as soon as possible. If the pain is severe, the temperature is high and the condition is rapidly deteriorating, urgent medical help is required.

Main

  • Kidney inflammation is more often bacterial: it affects the calyces and the renal pelvis, managed by a nephrologist, and when urine is retained a urologist is brought in.
  • Urine retention is the key cause: stones block the flow of urine and injure the walls, opening the way for bacteria to reach the tissue.
  • The acute process begins suddenly: lower back pain, fever with chills, frequent painful urination, cloudy urine.
  • Examination confirms the inflammation: urinalysis, urine culture, blood test, kidney ultrasound, and if necessary computed tomography.
  • Prevention of flare-ups: drinking regimen, timely emptying of the bladder, hygiene, treatment of bladder infections, check-ups with a urologist.

What is pyelonephritis

Pyelonephritis is an inflammation of the kidney, which is most often caused by bacteria that enter the organ from the bladder or through the bloodstream. Below is an explanation of what happens during such inflammation, what circumstances provoke it, and who is affected by it more often.

What happens in the body

The kidney is a paired organ that filters the blood and removes excess fluid along with metabolic products in the form of urine. When bacteria penetrate the kidney tissue, inflammation begins there, and the function of the organ in that area is disrupted. The infection can ascend from below, from the bladder through the ureter, or it can be carried through the blood from another focus of inflammation in the body. The inflamed tissue swells, presses on neighbouring structures and interferes with the normal outflow of urine. Because of this, urine stasis increases, and the bacteria multiply even more actively, maintaining the inflammation. The disease can run an acute course, or it can become chronic and require constant medical supervision. If the cause is not identified in time, the inflammation recurs and gradually damages the kidney tissue.

What causes it to develop

  • Impaired outflow of urine from the kidney: urine stasis creates conditions for the multiplication of bacteria and maintains the inflammation, so it is important to eliminate the cause of the stasis.
  • Kidney stone disease: stones block the path of urine and injure the walls of the urinary tract, opening the way for bacteria to reach the kidney tissue.
  • Reduced immunity: the body's weakened defences hold back bacteria less effectively, and they take hold in the kidney more easily, causing inflammation.
  • Diabetes mellitus: elevated sugar levels change the properties of urine and weaken local defences, which is why the infection takes hold more often.
  • Instrumental interventions on the urinary tract: examinations and procedures involving the insertion of an instrument can introduce bacteria, so the condition is monitored afterwards.

Who is affected more often

Kidney inflammation is more common in people who already have an obstruction to the outflow of urine or weakened body defences. Kidney stones and other outflow disorders create stasis, and this directly increases the risk of inflammation. Diabetes mellitus and reduced immunity make the body more vulnerable to bacteria that have entered the kidney. Those who have undergone instrumental interventions on the urinary tract are singled out separately: during such procedures, bacteria can penetrate deeper. In women, the ureter is shorter, so infection from the bladder ascends more easily than in men. In older men, changes in the prostate gland are added to this, which make the outflow of urine more difficult. If a person falls into a risk group, they should discuss monitoring with a doctor so as not to miss the onset of inflammation.

What symptoms can occur?

The symptoms of pyelonephritis depend on the form and severity of the inflammation, so noticing the disease can be difficult. An acute process usually begins suddenly, while a chronic one can proceed for a long time with blurred signs.

How it is noticed at the very beginning

At the beginning, pyelonephritis often manifests as general malaise, which is easily put down to fatigue or a cold. A person feels run-down, has a slight chill and reduced ability to work, without linking this to the kidneys. A dull pain appears in the lower back on one side, which is taken as a consequence of sitting for a long time. The temperature may rise only slightly, but it lasts longer than usual and is poorly explained. Urination becomes more frequent, sometimes with unpleasant sensations, which is also rarely paid attention to. Gradually the urine becomes cloudy and acquires an unpleasant smell, which is noticeable already at a glance. If such signs persist for several days, it is worth seeing a doctor without waiting for the pain to worsen.

Signs that occur most often

  • Pain in the lower back: felt on one or both sides, may be dull or aching and worsens with movement.
  • Temperature and chills: a rise in temperature is accompanied by chills, which are difficult to bring down and return again.
  • Urination: urges become frequent and painful, which noticeably changes the usual rhythm of the day.
  • Cloudy urine: it loses its transparency and acquires an unpleasant smell, which is visible without additional tests.
  • Nausea and malaise: weakness and nausea appear, because of which the condition is easily mistaken for poisoning.

When to seek help urgently

When to seek help urgently
SignHow urgentWhat to do
Pain in the lower back and temperatureAs soon as possibleSee a doctor
Severe pain in the lower backUrgentlyCall an ambulance
High temperatureUrgentlyDo not wait, call a doctor
Rapid deterioration of the conditionUrgentlyCall an ambulance
Chills and nausea togetherAs soon as possibleMake an appointment with a doctor

Examinations and tests

Examination for pyelonephritis is based on complaints, physical examination and laboratory data. Below are the investigations that help confirm inflammation and clarify its cause.

How the examination begins

The examination begins with a conversation, during which the doctor collects complaints and clarifies the history of past illnesses. Then they perform a physical examination, paying attention to tenderness in the lumbar region and the person's general condition. This information allows the doctor to suspect kidney involvement and choose the necessary investigations. To confirm the diagnosis, laboratory and instrumental methods are prescribed, each of which addresses its own task. A general urine test shows signs of inflammation, while a culture helps identify the causative agent. A general blood test reflects the activity of the inflammatory process in the body. Ultrasound examination of the kidneys reveals changes in their structure, and computed tomography clarifies details if necessary. Keep all results and discharge summaries so that at a follow-up appointment the doctor can see the dynamics.

What is prescribed and what it shows

What is prescribed and what it shows
InvestigationWhat it showsWhen it is prescribed
General urine testSigns of inflammationWhen pyelonephritis is suspected
Urine cultureThe causative agent of infectionTo clarify the cause of inflammation
General blood testActivity of inflammationTo assess the general condition
Ultrasound examination of the kidneysChanges in kidney structureTo assess the condition of the organ
Computed tomographyDetails of changesWhen clarification is necessary

What to prepare for the appointment

  • Discharge summaries: take previous doctors' conclusions to show how the disease developed and which investigations have already been carried out.
  • Test results: collect all urine and blood tests, including old ones, so that the doctor can assess changes in the values over time.
  • List of complaints: write down when the pain appeared, how the temperature changed and what is bothering you now, so that you do not forget anything at the appointment.
  • Past illnesses: list operations, injuries and chronic conditions, as they influence the choice of investigations and the assessment of the kidneys' condition.
  • Questions for the doctor: formulate in advance what is unclear about the diagnosis and further steps, so that the appointment is productive.

Which doctor should I see?

This section explains which doctor patients are referred to for pyelonephritis, what happens at the first appointment and what areas of care it involves. Below are guidelines for choosing a specialist and understanding how follow-up is organised.

Which specialist manages this condition

Pyelonephritis is managed by a nephrologist, and if urine outflow is impaired, a urologist is involved. The nephrologist deals with the inflammatory process in the kidney and selects antibacterial therapy taking into account the patient's condition. A urologist is needed when the cause lies in impaired patency of the urinary tract, for example with a stone or a narrowing. If a specialist is not available nearby, at the first stage care is provided by a physician or a general practitioner. They assess the severity of the condition and decide whether hospitalisation is required or outpatient follow-up is possible. At the appointment the doctor clarifies the complaints, medical history and previously ordered tests in order to determine further management. With severe pain, high temperature or signs of intoxication, care is more often provided in hospital under round-the-clock observation. The patient should bring all available test results and reports — this speeds up the decision on the route of care.

What treatment consists of

  • Selection of antibacterial therapy: the doctor chooses an agent taking into account the causative organism and the patient's condition; this is the basis for eliminating the infection.
  • Pain relief and temperature reduction: symptomatic care as prescribed by the doctor eases the condition and allows treatment to continue calmly.
  • Abundant drinking: maintained in the absence of contraindications, it helps restore urine outflow and reduce the load on the kidneys.
  • Monitoring of the condition and tests: regular monitoring shows how the body is responding and allows care to be adjusted in time.
  • Surgical intervention: used when urine outflow is impaired, when conservative care is ineffective without restoring the patency of the tracts.

What depends on the patient themselves

The result largely depends on how regularly the patient is followed up and follows the doctor's recommendations. Timely testing and repeat visits make it possible to notice deterioration before it becomes pronounced. If follow-up is interrupted when the patient feels better, the inflammation may return and become a low-grade form. Adhering to the drinking regimen agreed with the doctor supports urine outflow and reduces the risk of a repeat exacerbation. Not stopping prescriptions on one's own and not attempting to treat oneself directly affects the duration of care. Keeping simple records of temperature, pain and how one feels helps the doctor assess the dynamics more accurately at the appointment. If new complaints appear between visits, it is important not to wait for the scheduled appointment but to inform the doctor about them. The patient should find out in advance when to come for follow-up and which tests to repeat.

What helps prevent an exacerbation?

Everyday self-care and attention to the body's signals help prevent an exacerbation of pyelonephritis. Below are habits, observations and timing of visits that reduce the risk of recurrent infection.

What to change in your habits

Drinking regimen directly affects how often urine is renewed and how easily bacteria are washed out of the urinary tract. When there is not enough fluid, urine becomes concentrated, stays in the bladder longer, and it is easier for microbes to travel up the urinary tract. The bladder should be emptied promptly, without holding on for long, since stagnation creates a favourable environment for microorganisms to multiply. Urinary tract hygiene requires daily attention: washing with warm water without aggressive products, changing underwear, and being careful after using the toilet. Bladder infections must not be left untreated, because they often precede inflammation of the kidneys. Chronic diseases that impair overall health also affect resistance to infection, so keeping them under control is no less important. If there is stinging, heaviness in the lower back or a change in the colour of urine, a visit to the doctor should not be postponed.

What should be kept under control

  • Drinking regimen: a sufficient amount of fluid every day maintains the flow of urine and prevents bacteria from lingering in the tract.
  • Timely emptying: do not hold the urge for long and empty the bladder completely so as not to leave stagnation.
  • Urinary tract hygiene: daily washing and changing underwear reduce the entry of microbes into the urethra.
  • Treatment of bladder infections: see it through to the end so that inflammation does not rise to the kidneys.
  • Chronic diseases: keep them under supervision, since they weaken the body's defences.
  • Urologist check-ups: if you are predisposed, have them regularly, even when you feel well.

How often to see a doctor

Regular check-ups with a urologist are needed even when you feel well, if there is a predisposition to pyelonephritis. The doctor assesses how the urinary system is working, whether there are any obstacles to the outflow of urine and whether there is any smouldering hidden inflammation. Between visits, it is worth noticing changes: more frequent urges, discomfort when urinating, heaviness or aching sensations in the lower back. Such signs are easily put down to fatigue, but they are the first to speak of an incipient exacerbation. Chronic diseases require separate monitoring, since their course affects resistance to infection. If symptoms appear, a visit must not be postponed: seeking help early simplifies observation and helps avoid complications. Planned check-ups should be agreed with the doctor in advance so as not to miss them when you feel well.

What is worth remembering

Pyelonephritis is a condition in which it is important not so much to memorise individual signs as to understand the general order of actions. Below are collected conclusions that help make the right decision and not harm yourself.

Main conclusions

Pyelonephritis requires careful attention to your own condition, because its course can be different and not always obvious. Pyelonephritis can proceed latently for a long time, manifesting only as weakness, heaviness in the lower back or a change in well-being without pronounced pain. Pyelonephritis is dangerous not so much from the inflammation itself as from complications, if it is not recognised in time and observation by a specialist is not started. Pyelonephritis is often confused with an ordinary cold or radiculitis, so people spend a long time doing the wrong thing. Pyelonephritis is not treated independently, because inappropriate measures can erase the picture of the disease and make the doctor's work more difficult. Pyelonephritis in people with chronic diseases or a weakened immune system is more severe and requires closer monitoring. Pyelonephritis is a reason not to postpone a visit to the doctor and not to wait for the condition to improve on its own. The support in the decision is calm observation of your body and timely seeking help, rather than attempts to endure it.

Portal Editorial TeamMedical editorial team

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Questions and answers

Answered by the article’s medical editor.

Can pyelonephritis develop in childhood?

Yes, pyelonephritis also occurs in children, especially in those who frequently suffer from bladder infections. In young children it often manifests only as fever, restlessness and refusal to eat, without complaints of lower back pain. Therefore, in case of unexplained fever in a child, the doctor will certainly check the urine and refer to a nephrologist or urologist.

How does the course of pyelonephritis differ in the elderly?

Usually in the elderly the symptoms are blurred and the disease is recognised later. The temperature may be low-grade or absent altogether, while weakness, confusion and loss of appetite come to the fore. Because of this, the inflammation is often mistaken for age-related changes, so when well-being deteriorates it is important to check the kidneys.

What follow-up tests should be repeated after treatment?

Usually follow-up includes a repeat urine test and a full blood count, sometimes an ultrasound examination of the kidneys. The doctor assesses whether the signs of inflammation have resolved and whether there are any obstacles to urine outflow. The timing of follow-up checks is set by the specialist, and they should be kept even if you feel well.

Can one work and exercise with pyelonephritis?

During the acute period — no, rest and medical supervision are needed. When the condition improves, the load is returned gradually, avoiding hypothermia and heavy training. Work involving prolonged standing or night shifts should be discussed with the doctor so as not to provoke an exacerbation.

How does pyelonephritis affect pregnancy?

This condition requires special attention, as urinary tract infection occurs more often during pregnancy. Inflammation of the kidneys can affect the course of pregnancy, so follow-up is carried out jointly by a urologist and an obstetrician-gynaecologist. At the first signs of malaise, the expectant mother should immediately inform the doctor.

What are the dangers of pyelonephritis if left untreated?

It can lead to serious complications, up to severe inflammation and impaired kidney function. Constant inflammation gradually damages the kidney tissue, and the infection can spread further through the body. Therefore, if pyelonephritis is suspected, it is important not to postpone a visit to the specialist and not to try to endure it.

When should an ambulance be called for pyelonephritis?

Urgently — for severe lower back pain, high temperature and rapid deterioration of the condition. Chills together with nausea and weakness are also a reason not to wait for a scheduled appointment. In such cases, care is provided in hospital, so one must not delay calling the doctor.

Which doctor should one consult first?

A physician or general practitioner, if no specialist is available nearby. They will assess the condition and decide whether the help of a nephrologist or urologist is needed. A urologist is involved when the cause is impaired urine outflow, while a nephrologist manages the inflammation of the kidney itself.

How long should one be followed up by a doctor after an exacerbation?

Usually follow-up continues for a long time, even after the well-being improves. The doctor schedules follow-up checks and monitors that the inflammation does not return in a hidden form. Follow-up should not be interrupted when feeling well, as an exacerbation may recur.

Can recurrent exacerbation of pyelonephritis be prevented?

Yes, much depends on everyday habits. Sufficient drinking, timely emptying of the bladder and hygiene reduce the risk of recurrent infection. It is also important to complete treatment of bladder infections and to keep chronic diseases that weaken the body's defences under control.