Gallstone disease

Gallstone disease is the formation of stones in the gallbladder and bile ducts. Stones form from cholesterol, bile pigments and salts, remain silent for a long time, and then manifest as heaviness in the right hypochondrium, a bitter taste in the mouth and attacks of pain after fatty food. A gastroenterologist is involved in diagnosis and treatment, and a surgeon is brought in if necessary. If such complaints appear, a doctor's consultation and examination are needed.

Which doctorGastroenterologist, also a surgeon
UrgencyRoutine appointment
Reviewed byMedical editorial team
Updated

If pain appears in the right hypochondrium or nausea after eating, make an appointment with a gastroenterologist. If the pain is severe, does not go away, and is accompanied by jaundice, fever or vomiting, urgent medical help is needed.

Key points

  • Stones form from cholesterol and salts and may cause no symptoms for years.
  • An attack is triggered by fatty food: pain in the right hypochondrium, nausea, a bitter taste in the mouth.
  • The first diagnostic step is an ultrasound of the abdominal organs.
  • The condition is managed by a gastroenterologist; with recurrent attacks, a surgeon is involved.
  • Yellowing of the skin and eyes, fever or unrelenting pain require calling an ambulance.

What is gallstone disease

Gallstones are a condition in which dense stones made of cholesterol or salts form in the gallbladder. The stones may cause no trouble for years, but sometimes they cause pain and inflammation.

What happens in the body

Bile is produced by the liver and accumulates in the gallbladder, from where it passes into the intestine to digest fats. Stones form when the composition of bile is disturbed: it contains too much cholesterol or too little of the substances that keep it dissolved. Stagnation of bile in the gallbladder also contributes to stone formation, because the fluid stagnates for a long time and thickens. The dense formations may be as small as grains of sand or reach the size of a large cherry. While the stone lies quietly, a person usually feels nothing and learns about it by chance. When the stone shifts and gets stuck in the duct, pain and inflammation occur. Therefore, when heaviness or pain appears in the right hypochondrium, it is important not to postpone a visit to the doctor.

What causes it to develop

  • Hereditary predisposition: if close relatives have had gallstones, the risk is higher, because metabolic characteristics are passed down through the family.
  • Excess weight and rapid weight loss: extra kilograms change the composition of bile, and rapid weight loss increases stagnation and thickening of the fluid in the gallbladder.
  • A diet with a lot of fats and little fibre: fatty food raises cholesterol levels, while a lack of vegetables and grains deprives bile of the substances that keep it in solution.
  • Female sex and age-related changes: women have stones more often, and with age metabolism slows down and bile becomes thicker.
  • Certain diseases of the intestine and liver: when they are disturbed, absorption and the composition of bile change, which creates conditions for the formation of dense clots.
  • Taking certain medicines: some remedies affect cholesterol metabolism and gallbladder motility, so any long-term use should be reported to a doctor.

Who faces this more often

Gallstones are more often detected in women past middle age, especially those who are overweight. Men also have stones, but noticeably less often, and this is usually linked to heredity or concomitant metabolic diseases. People whose close relatives have had gallbladder surgery are in the group requiring increased attention. A diet rich in fatty foods and with few vegetables gradually changes the composition of bile for the worse. Drastic attempts to lose weight in a short time also raise the risk, because the gallbladder empties unevenly. Age-related metabolic changes make bile thicker, and this is noticeable in older people. If you have such characteristics, it is reasonable to discuss them with a doctor at your next check-up.

What symptoms occur?

Gallstones can remain silent for a long time, and then they are discovered incidentally during an examination. When a stone blocks the duct, characteristic attacks appear, by which the condition is recognised.

How it is noticed at the very beginning

At an early stage, gallstone disease most often produces no symptoms at all, and the person considers themselves completely healthy. Gallstones in the gallbladder are often found during an examination for a completely different reason. Occasionally there is a feeling of heaviness in the right hypochondrium, which is easily attributed to fatigue or a heavy supper. After fatty food, nausea may occur, and a bitter taste remains in the mouth. Abdominal bloating and discomfort under the pit of the stomach are also attributed to dietary indiscretions. Such sensations pass on their own, so help is rarely sought at this stage. If the unpleasant sensations recur after eating, it is sensible not to postpone a visit to a gastroenterologist.

Symptoms that occur most often

  • Pain in the right hypochondrium: occurs in attacks, often after fatty food, and may radiate under the pit of the stomach.
  • Nausea and bitterness in the mouth: appear together with the discomfort and indicate bile stasis in the ducts.
  • Abdominal bloating: felt as distension, worsens after eating and often accompanies an attack.
  • Yellowing of the skin and eyes: noticeable when the outflow of bile is impaired and requires a doctor's attention.
  • Dark urine and pale stools: change their usual colour when bile stops entering the intestine.
  • Fever with inflammation: is a reason for an urgent visit, not for watching at home.

When to seek help urgently

When to seek help urgently
SymptomHow urgentWhat to do
Pain in the right hypochondrium after eatingRoutine visitMake an appointment with a gastroenterologist
Nausea after fatty foodRoutine visitMake an appointment with a gastroenterologist
Severe pain that does not go awayEmergency careCall an ambulance
Yellowing of the skin and eyesEmergency careCall an ambulance
Fever or vomitingEmergency careCall an ambulance

Examinations and tests

Examination for gallstones begins with a conversation and a physical examination, and is then confirmed by instrumental and laboratory methods. Below is a description of which investigations are used and what information each of them provides.

How the examination begins

When gallstones are suspected, the doctor begins the examination by asking about the complaints and examining the abdomen. During the conversation, they clarify when the pain appeared, where it is located and what it is associated with. During the examination, the doctor palpates the abdomen, paying attention to tender areas and muscle tension. These actions help to form a preliminary idea of the state of the gallbladder. To confirm the diagnosis, instrumental and laboratory investigations are prescribed. Ultrasound is usually the first step, as it shows stones and the walls of the gallbladder well. If the data are insufficient, more precise imaging methods are used. Therefore, it is worth coming to the appointment prepared to undergo several consecutive procedures.

What is prescribed and what it shows

What is prescribed and what it shows
ExaminationWhat it showsWhen it is prescribed
Ultrasound of the abdominal organsStones and the state of the gallbladderFor the first complaints of pain
Blood testsSigns of inflammation or impaired bile outflowTo assess the general condition
Computed tomographyClarifies the location of the stonesWhen the ultrasound picture is unclear
Magnetic resonance imagingShows the bile ducts in detailWhen stones in the ducts are suspected
Endoscopic retrograde cholangiopancreatographyAssesses the state of the ductsWhen there are signs of bile stasis

What is worth preparing for the appointment

  • Discharge summaries from the medical history: take all documents about previous visits, they will help the doctor see the dynamics and avoid repeating investigations already undergone.
  • Results of ultrasound and other images: bring the films and reports so that the specialist can assess changes in the gallbladder and ducts in comparison.
  • Blood tests: prepare recent and previous results, they show signs of inflammation or impaired bile outflow at different periods.
  • List of complaints: write down when and how the pain occurs, what provokes it, this will help describe the condition more precisely at the appointment.
  • Questions for the doctor: formulate in advance what you want to clarify about your condition and the upcoming examinations, so as not to forget anything important.

Which doctor should I see?

This section explains which doctor to consult for gallstones, what happens at the first appointment and what areas of care make up the treatment.

Which specialist manages this condition

Gallstones are managed by a gastroenterologist, and a surgeon is involved if necessary. The gastroenterologist provides follow-up, assesses symptoms and selects a diet if the stones do not cause symptoms. A surgeon is needed when attacks recur or complications appear that require surgery. If there is no specialist nearby, start with a general practitioner: they will examine you and refer you to the right specialist. Notes about attacks, the results of previous examinations and a list of medications taken will help the doctor understand the situation faster. At the first appointment, the specialist clarifies how long ago and how often the pain occurs and whether it is related to food. Then they decide whether follow-up is sufficient or surgery is required.

What the treatment consists of

  • Diet: limiting fatty and fried food reduces the load on the gallbladder and decreases the frequency of attacks.
  • Follow-up with a gastroenterologist: regular monitoring of the condition allows changes to be noticed in time and the approach to be adjusted.
  • Medication: in certain cases the doctor selects agents to dissolve the stones, but this is not suitable for everyone.
  • Surgery: removal of the gallbladder is discussed for frequent attacks or complications, when other measures are insufficient.
  • Repeat examinations: their frequency is determined by the doctor, and it affects how promptly new changes are detected.

What depends on the patient themselves

The result of follow-up for gallstones largely depends on the regularity of visits to the doctor. If a person attends examinations according to the schedule set, the specialist sees the dynamics and changes the approach in time. Missed appointments mean that repeat attacks take the doctor by surprise, and complications are detected later. Following the diet agreed with the gastroenterologist noticeably reduces the number of flare-ups and makes everyday life easier. Notes about when and after what food the pain occurred give the doctor an accurate picture instead of approximate recollections. If new complaints appear, they should be reported at the nearest appointment rather than postponed until a routine visit. A patient who honestly describes their condition and follows the recommendations helps the doctor find a suitable solution. Regularity and attentiveness to oneself are the part that no specialist can replace.

What helps prevent an exacerbation?

Preventing an exacerbation of gallstone disease is helped by everyday lifestyle, not only by visits to the doctor. Below, we look at which habits and observations really reduce the risk, and how often monitoring is needed.

What is changed in habits

Regular physical activity and a balanced diet are among the main habits influencing the course of gallstone disease. Daily walking, swimming or housework support metabolism and help the body use energy more steadily. A sufficient amount of fibre in the diet — vegetables, grains, pulses — improves bowel function and reduces bile stasis. Moderate fat consumption is important because fatty food makes the gallbladder contract sharply and provokes an attack. Sharp fluctuations in weight, especially rapid weight loss or weight gain, increase the risk of new stones forming. Timely treatment of bowel and liver diseases removes additional strain on the biliary tract. It is worth discussing your usual diet and level of activity with a doctor so as to change them gradually and without harm.

What should be kept under control

  • Body weight: its stability is more important than any sharp changes, because rapid weight loss or gain increases the risk of exacerbation.
  • Fibre in the diet: vegetables, grains and pulses should be present daily, since fibre supports normal bile outflow.
  • Amount of fats: fatty food is best limited, because it causes sharp contraction of the gallbladder and an attack.
  • Physical activity: regular feasible exercise helps keep weight and metabolism in a stable state.
  • Condition of the bowel and liver: their diseases should be treated in good time so that they do not aggravate the course of the disease.
  • How you feel: any new or increased sensations in the right hypochondrium are a reason not to postpone a visit to the doctor.

How often to see a doctor

Even with good health, gallstone disease requires regular monitoring by a doctor, not only visits when there is pain. Stones may give no sign of themselves for years, but may change position and size, so a calm period does not cancel out observation. The doctor assesses complaints, examines and, if necessary, prescribes tests in order to notice changes before exacerbation. If heaviness, a bitter taste in the mouth or discomfort after eating appear, the visit should not be postponed. With a stable condition, routine check-ups at the frequency determined by the doctor are sufficient. Missed check-ups lead to exacerbation taking you unawares and requiring more serious help. It is worth clarifying a convenient monitoring schedule with the doctor in advance and sticking to it.

What is worth remembering

The discussion of gallstone disease ends with several conclusions that help make a balanced decision. They concern how to approach the condition, what not to put off, and what to rely on.

Main conclusions

Gallstone disease is often asymptomatic, and the detection of stones during an incidental examination does not in itself mean that something needs to be done urgently. The decision on the approach is made by the doctor, comparing the complaints, the results of examinations and the person's general condition. The danger is posed not by the stones themselves, but by their movement and blockage of the ducts, which causes an attack. Such an attack is usually accompanied by severe pain in the right hypochondrium, nausea and a bitter taste in the mouth. If the pain persists for a long time, the temperature rises, or yellowing of the skin and eyes appears, one must not wait. With gallstone disease, it is dangerous to self-treat and try to expel the stones with home remedies. Discussing with the doctor, monitoring and timely seeking help during an attack are what one should rely on.

Portal Editorial TeamMedical editorial team

Covers what does not belong to a single specialty: how an appointment works, what to bring with you, how to read a referral. Every text is reviewed by a relevant doctor before publication.

PublishedUpdatednot updated

The portal does not provide medical services and does not replace a consultation with a doctor. The information on condition pages is for reference only.

Who treats it

Available times and booking are on the doctor’s card.

Portrait photo of a doctor, appointment in Almaty

Imanbekova Zhanna Berdibekovna

Gastroenterologist, Cardiologist, Pulmonologist
1 more, Therapist

Why you can trust this doctor

  • Work experience42 years
  • Who they seeChildren aged 18 years and over and adults

Price on request

Zdorovya-DesMed, ul. Kunaeva, 75

Choose a convenient date and time

Portrait photo of the doctor, appointment in Almaty

Why you can trust this doctor

  • Work experience8 years
  • Who they seeChildren aged 5 years and over and adults

Price on request

ESM-Clinic, pr. Seyfullina, 580 (1-y etazh)

Choose a convenient date and time

Portrait photo of the doctor, appointments in Almaty

Gotskaya Angelina Nikolaevna

Gastroenterologist, Therapist, Infectious disease specialist
1 more, Family doctor

Why you can trust this doctor

  • Work experience21 years
  • Who they seeChildren from birth and adults

25 000 ₸

Prima Medical Group, ul. Luganskogo, 54/1, Medeu district

Choose a convenient date and time

Why you can trust this doctor

  • Work experience36 years
  • Who they seeChildren from birth and adults

Price on request

Choose a convenient date and time

Why you can trust this doctor

  • Work experience21 years
  • Who they seeChildren aged 18 years and over and adults

Price on request

Choose a convenient date and time

Portrait photo of a doctor, appointment in Almaty

Why you can trust this doctor

  • Work experience41 years
  • Who they seeChildren aged 15 years and over and adults

Price on request

Avtorskaya meditsina, ul. Karasay batyra, 152

Choose a convenient date and time

Questions and answers

Answered by the article’s medical editor.

Does gallstone disease occur in children?

Usually not, gallstones are rare in children. They are more often found in hereditary blood diseases or after prolonged fasting. If a child has recurring pain in the abdomen on the right, a paediatrician examines them and, if necessary, refers them to a gastroenterologist.

How does the course of the disease differ in the elderly?

In the elderly it more often runs an erased course, without vivid attacks. The pain may be mild, and inflammation develops unnoticed, so the condition is detected later. Because of this, elderly people should discuss even minor discomfort in the right hypochondrium with a doctor.

Can one do sports with stones in the gallbladder?

Usually yes, moderate exercise is not prohibited. Calm walking, swimming and gymnastics support metabolism and help maintain weight. Sharp bends, lifting weights and abdominal exercises are best discussed with a doctor so as not to provoke an attack.

Is one allowed to work with gallstones?

As a rule, yes, if there are no frequent attacks. With a calm course, a person continues their usual work and does not limit themselves. If attacks recur or complications have appeared, the question of exercise and regimen is decided by the doctor.

Can one become pregnant and carry a child with stones in the gallbladder?

Usually yes, pregnancy is possible with this condition, but requires monitoring. The stones themselves do not interfere with conception and carrying, however hormonal changes slow the outflow of bile. Therefore, the expectant mother should tell the gastroenterologist and obstetrician about her condition in advance.

What complications occur with this disease?

The most common are inflammation of the gallbladder and blockage of the ducts. A stone can block the outflow of bile, then jaundice, fever and severe pain appear. Less often the pancreas is affected, so such signs require urgent help.

When should one call an ambulance for pain rather than go to a doctor?

An ambulance is called if the pain is severe and does not pass. Yellowing of the skin and eyes, high temperature, repeated vomiting and severe weakness are also reasons. In these cases one cannot wait for a scheduled appointment, help is needed immediately.

How long can one be monitored by a doctor without surgery?

Monitoring is possible for years if the stones do not bother. The doctor assesses the complaints and, if necessary, prescribes an examination to notice changes. With frequent attacks or complications, they discuss with the patient the transition to surgical treatment.

Can one live with stones all one's life and do nothing?

Yes, with an asymptomatic course many live with them for a long time. For years the stones do not make themselves known and do not require intervention. But this does not cancel monitoring: the position and size of the stones can change, so visits to the doctor are needed.

Does diet affect the size and number of stones?

Yes, the diet affects the composition of bile and the course of the disease. An abundance of fatty food and a small amount of vegetables and grains worsen the outflow of bile and increase the risk of an attack. Sharp fluctuations in weight are also unfavourable, so it is worth changing the diet gradually and in agreement with the doctor.